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Tacrolimus Conversion

BC Transplant is converting from Prograf to Sandoz immediate release tacrolimus for BC Transplant patients.

In spring 2019, BC Transplant and BC Renal completed a joint Request for Proposal (RFP) for immediate release tacrolimus. Following an extensive review by a multi-disciplinary team of representatives, the award was given to Sandoz Canada for their immediate release tacrolimus product. As a result of the new contract award, BC Transplant patients will start to receive Sandoz tacrolimus rather than Prograf. 

Important dates to note

The projected medication conversion will begin in fall 2019 and is anticipated to complete by March 31, 2020.

Nov. 4, 2019

Initiation of de novo transplant patients on Sandoz tacrolimus to occur at the provincial transplant centres at BC Children's Hospital and Vancouver General Hospital.

Nov. 18, 2019

Conversion of current transplant patients from Prograf to Sandoz tacrolimus will commence at Interior Health Authority and Northern Health Authority clinics in Kamloops, Kelowna, Penticton, Trail and Prince George.

Jan. 6, 2020

Initiation of de novo transplant patients on Sandoz tacrolimus will commence at St. Paul's Hospital.

Jan. 6, 2020

Conversion of current transplant patients will commence at all remaining clinis at Vancouver General Hospital, BC Children's Hospital, St. Paul's Hospital, Surrey, Victoria and Nanaimo.

To see the full timeline of dates, please refer to the Information Sheet below.


Resources for health professionals

BC Transplant has developed a number of resources and tools to support clinicians through the change. 

 This communication was distributed to transplant clinics and partner pharmacies and provides the background and benefits of the conversion as well as important dates.

This communication was distributed to transplant clinics and partner pharmacies and provides the background and benefits of the conversion as well as important dates.

Click HERE.

This workflow guide is a framework for the clinical processes and actions to be performed by clinicians to ensure effective care for patients during the inpatient de novo period.

Click HERE.


‎This workflow guide is a framework for the clinical processes and actions to be performed by clinicians to ensure effective care for patients during the conversion period.

Click HERE.

This template is to be used by clinics to communicate with pharmacists.

Click HERE.

 

This checklist is to be used by clinics to document each step of conversion.

Click HERE.‎

 

This bibliography is a list of selected clinical studies that evaluate the safety and efficacy of converting transplant patients from Prograf to alternate brands of immediate release tacrolimus.

Click HERE.

‎Frequently asked questions about the tacrolimus conversion process.

Click HERE.

 


Resources for patients

Full resources for patients are available on the patient tacrolimus conversion webpage HERE.

Patient information sheet on tacrolimus brand switch.

Click HERE.

(Other languages available to download on patient webpage.)‎

This poster provides information about the tacrolimus conversion to patients. It can be downloaded and printed to post in your clinic.

Click HERE.


SOURCE: Tacrolimus Conversion ( )
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